Chief may refer to:
Galen Tyrol (commonly referred to as The Chief) is a character on the television series Battlestar Galactica. Tyrol is responsible for the maintenance of the Vipers and Raptors aboard Battlestar Galactica. After the events of the miniseries, he was the ship's highest-ranking non-commissioned officer at rank of Senior Chief Petty Officer.
Galen Tyrol is played by Aaron Douglas, who originally auditioned for the role of Lee Adama before that role went to English actor Jamie Bamber.
At the start of the series, Tyrol is romantically involved with Lieutenant Sharon "Boomer" Valerii aboard Galactica, who is, unbeknownst to either Tyrol or herself, a Cylon. Once Sharon's true nature is revealed when she attempts to assassinate then-Commander Adama, Tyrol is accused of being a Cylon and is thrown into the brig with Sharon. He claims he hates her and orders her to keep her distance, but when Sharon is shot and killed by Cally, he mourns her and reveals his true affection for her. Tyrol is "proven" not to be a Cylon - for the time being - and resumes his job. Discovering the existence of Caprica-Valerii (who is pregnant and in love with Helo) confuses him, especially with Galactica-Valerii's death still haunting him.
In heraldic blazon, a chief is a charge on a coat of arms that takes the form of a band running horizontally across the top edge of the shield. Writers disagree in how much of the shield's surface is to be covered by the chief, ranging from one-fourth to one-third. The former is more likely if the chief is uncharged, that is, if it does not have other objects placed on it. If charged, the chief is typically wider to allow room for the objects drawn there.
The chief is one of the ordinaries in heraldry, along with the bend, chevron, fess, and pale. There are several other ordinaries and sub-ordinaries.
The chief may bear charges and may also be subject to variations of the partition lines. The chief may be combined with another ordinary, such as a pale or a saltire, but is almost never surmounted by another ordinary. The chief will normally be superimposed over a bordure, orle and tressure, if they share the same shield.
A chief combined with a pale.
HSE may refer to:
Heparanase, also known as HPSE, is an enzyme that acts both at the cell-surface and within the extracellular matrix to degrade polymeric heparan sulfate molecules into shorter chain length oligosaccharides.
The protein is originally synthesised in an inactive 65 kDa proheparanase form in the golgi apparatus and transferred to late endosomes/lysosomes for transport to the cell-surface. In the lysosome it is proteolytically processed into its active form. Proteolytic processing results in the production of three products,
The 8 kDa and 50 kDa fragments form a heterodimer and it is this heterodimer that constitutes the active heparanase molecule. The linker protein is so called because prior to its excision it physically links the 8 kDa and 50 kDa proheparanase fragments. Complete excision of the linker peptide appears to be a prerequisite to the complete activation of the heparanase enzyme.